Isothiazolinone can be said to be the most widely used bactericidal and algaecidal in domestic and abroad, the highest performance bactericidal preservatives. It's actually a mixture, mostly CMIT and MIT, in a ratio of about 3:1.

Isothiazolinone is very safe, close to non-toxic, but there is a certain irritation to the skin, especially the original solution as far as possible not to contact the skin, otherwise some people may have a more intense allergic reaction. So, the European rules: if water products cotains isothiazolinone active ingredients more than 15ppm, the product must be labeled as dangerous goods, which is common CL-MIT 1.5%, the recommended dosage can not exceed 1.0‰.

10 PPM kathon can effectively kill most microorganisms, but now we need much more, the reason actually very simple, main is to use in the wrong way, just add algae fungicidal 1.0 ‰, in fact, a lot of times, Kathon became more and more resistant.

In view of the above situation, we can use the following methods to avoid regulatory or drug resistance problems when designing the formulation and application recommendation of kasone: It is suggested to use the complex type of casone, for one thing, to avoid the dosage of casone exceeding the regulations, such as Thor 1209 and Combat series preparations, and for another thing, the combination of multi-component fungicides can reduce the probability of drug resistance of casone.

Everything has two sides, Kathon sterilization efficiency is very high, speed is also fast, but Kathon has two major shortcomings :(1) casson is afraid of heat, try to add less than 45℃; (2) Keep away from alkaline environment, generally lower than pH 8.5 use.

Preservatives on the market：

1, Isothiazolinone (CMIT+MIT=3:1), usually light yellow or light blue transparent liquid (magnesium salt or copper salt). In order to avoid undesirable phenomena such as salting out of water-based products caused by divalent salt, many companies have specially developed sodium salt casson (excluding divalent metal salt), such as Combat MV.

2, Isothiazolinone (CMIT+MIT=1:9), generally light yellow transparent liquid, the product is more durable corrosion resistance, such as Combat BV88.

3, CMIT/MIT + formaldehyde, formaldehyde contributes to the stability of CMIT/MIT, enhance the upper protection function of the tank, the combination of high cost performance, in the normal use of concentration, formaldehyde in the paint will not exceed the standard. Such as fungicide HF, 402F and so on.

4, CMIT/MIT + formaldehyde release agent, compared with free formaldehyde, formaldehyde release agent is more mild. There are many formaldehyde releasing agents, such as DMDMH, EGF and so on.

5, CMIT/MIT + Broonopol, contributes to the stability of casson, bactericidal spectrum is wider. But pay attention to the ratio of the two collocation. This is a typical compound fungicide, such as Thor1209, Combat CMB 15.

6, CMIT/MIT +BIT, gray or milky white dispersion, zero VOC, the change of preparation not only reduces the allergic phenomenon of casson and other skin, but also expands the application of PH value. The most important thing is the perfect combination of the rapid sterilization of CMIT/MIT and the durable corrosion protection of BIT, which has a strong synergistic effect and is worthy of recommendation.